Cystic Fibrosis Newborn Screening Program
The Cystic Fibrosis Newborn Screening Program at Children’s National Hospital is designed to quickly and accurately evaluate babies with abnormal cystic fibrosis (CF) screening results so that, if needed, care can begin as early as possible. We follow national newborn screening guidelines while focusing on what matters most to families: clear communication, expert medical care and thoughtful emotional support. Our team works closely with parents every step of the way, answering questions and helping you understand what the results mean for your child and your family.
What is cystic fibrosis?
Cystic fibrosis is a genetic condition that causes thick, sticky mucus to build up in the lungs and other organs, making breathing and digestion harder. Early diagnosis helps doctors manage symptoms and protect a child’s health from the start.
The Cystic Fibrosis Newborn Screening Process
1. Review Newborn Screening Results
When a newborn screening result is abnormal, the CF team at Children’s National is notified and reviews the results to determine next steps based on national guidelines. Your child’s pediatrician is also informed, and families are referred to Children’s National—sometimes by both the Department of Health and the primary care provider—to ensure timely care.
2. Specialized Clinical Evaluation
Infants are first seen via telemedicine by a Children's National provider experienced in cystic fibrosis and newborn screening. During this visit, the team completes a thorough assessment, reviews screening results, and offers education, guidance and support to address any questions or concerns.
3. Confirmatory Testing
When needed, sweat chloride testing—the most accurate test for diagnosing CF—is ordered right away. This testing is scheduled promptly to help confirm or rule out a diagnosis as quickly as possible.
4. Clear Communication and Next Steps
Results are shared with families. Each family receives a clear plan, whether that means reassurance, continued follow‑up or starting CF‑specific care if needed.
Preparing for A Sweat Test
A sweat test collects some of a patient's sweat to measure salt levels. It's a safe and reliable way to detect cystic fibrosis. See what it's like to get a sweat test at Children's National.
By emphasizing speed, expertise and communication, the Cystic Fibrosis Newborn Screening Program at Children’s National:
- Reduces unnecessary delays in diagnosis
- Alleviates parental anxiety during a vulnerable period
- Ensures accurate interpretation of complex screening results
- Facilitates early intervention when CF is confirmed
This program reflects our commitment to delivering timely, high-quality and family-centered care, ensuring that every infant with an abnormal CF newborn screening result receives the right evaluation at the right time.